跳转至内容
Merck
CN

SHMT1

serine hydroxymethyltransferase 1 (soluble)

别名:
CSHMT, SHMT
物种:
UniProtKB ID:
基因ID:
  • Human(6470) Summary: This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(20425) serine hydroxymethyltransferase 1 (soluble)
  • Rat(287379) serine hydroxymethyltransferase 1 (soluble)
  • chicken(416520) serine hydroxymethyltransferase 1 (soluble)
  • Zebrafish(394021) serine hydroxymethyltransferase 1 (soluble)
  • naked mole-rat(101726020) serine hydroxymethyltransferase 1 (soluble)
  • domestic guinea pig(100733584) serine hydroxymethyltransferase 1 (soluble)
  • sheep(443544) serine hydroxymethyltransferase 1 (soluble)
  • Domestic Rabbit(100009405) serine hydroxymethyltransferase 1 (soluble)
  • cow(509002) serine hydroxymethyltransferase 1 (soluble)
  • domestic cat(101086266) serine hydroxymethyltransferase 1 (soluble)
  • dog(489536) serine hydroxymethyltransferase 1 (soluble)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-SHMT1 antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-SHMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-SHMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SHMT1,
物种
human
MISSION® esiRNA, targeting mouse Shmt1,
物种
mouse