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Merck
CN

SF3B1

splicing factor 3b, subunit 1, 155kDa

别名:
Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155
物种:
UniProtKB ID:
基因ID:
  • Human(23451) Summary: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(81898) splicing factor 3b, subunit 1
  • Rat(84486) splicing factor 3b, subunit 1
  • domestic guinea pig(100723509) splicing factor 3b, subunit 1, 155kDa
  • cow(510177) splicing factor 3b, subunit 1, 155kDa
  • Zebrafish(446117) splicing factor 3b, subunit 1
  • naked mole-rat(101707227) splicing factor 3b, subunit 1, 155kDa
  • dog(488456) splicing factor 3b, subunit 1, 155kDa
  • domestic cat(101088016) splicing factor 3b, subunit 1, 155kDa
  • Horse(100070506) splicing factor 3b, subunit 1, 155kDa
  • Goat(100861148) splicing factor 3b, subunit 1, 155kDa
  • sheep(101121573) splicing factor 3b, subunit 1, 155kDa
  • chicken(424056) splicing factor 3b, subunit 1, 155kDa

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Antibodies

货号
说明
物种反应性
应用
Anti-SF3B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-SF3b155 (SAP 155) Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
immunocytochemistry
western blot
Anti-SF3B1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Anti-SF3B1, affinity isolated antibody,
物种反应性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Anti-SAP155/SF3b155 Antibody, serum, from rabbit,
物种反应性
bovine, human, mouse, rat
应用
immunoprecipitation (IP)
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SF3B1,
物种
human
MISSION® esiRNA, targeting mouse Sf3b1,
物种
mouse