跳转至内容
Merck
CN

RAPGEF2

Rap guanine nucleotide exchange factor (GEF) 2

别名:
CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, Rap-GEP, nRap GEP
物种:
UniProtKB ID:
基因ID:
  • Human(9693) Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]
  • Mouse(76089) Rap guanine nucleotide exchange factor (GEF) 2
  • Rat(310533) Rap guanine nucleotide exchange factor (GEF) 2
  • domestic guinea pig(100725060) Rap guanine nucleotide exchange factor (GEF) 2
  • naked mole-rat(101718791) Rap guanine nucleotide exchange factor (GEF) 2
  • sheep(101111578) Rap guanine nucleotide exchange factor (GEF) 2
  • Domestic Rabbit(100346752) Rap guanine nucleotide exchange factor (GEF) 2
  • dog(482670) Rap guanine nucleotide exchange factor (GEF) 2
  • domestic cat(101084954) Rap guanine nucleotide exchange factor (GEF) 2
  • Horse(100069003) Rap guanine nucleotide exchange factor (GEF) 2
  • cow(100139484) Rap guanine nucleotide exchange factor (GEF) 2
  • Zebrafish(557693) Rap guanine nucleotide exchange factor (GEF) 2
  • chicken(422418) Rap guanine nucleotide exchange factor (GEF) 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-RAPGEF2 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-RAPGEF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-RAPGEF2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human RAPGEF2,
物种
human
MISSION® esiRNA, targeting mouse Rapgef2,
物种
mouse