PCSK7
proprotein convertase subtilisin/kexin type 7
别名:
LPC, PC7, PC8, SPC7
物种:
Human PCSK7 (9159), Mouse Pcsk7 (18554), Rat Pcsk7 (29606), naked mole-rat Pcsk7 (101699616), Zebrafish pcsk7 (100009656), domestic cat PCSK7 (101086172), chicken PCSK7 (395455), domestic guinea pig Pcsk7 (100728543), sheep PCSK7 (101118814), Domestic Rabbit PCSK7 (100342422) ...展开
UniProtKB ID:
基因ID:
- Human(9159) Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq, Jul 2008]
- Mouse(18554) proprotein convertase subtilisin/kexin type 7
- Rat(29606) proprotein convertase subtilisin/kexin type 7
- naked mole-rat(101699616) proprotein convertase subtilisin/kexin type 7
- Zebrafish(100009656) proprotein convertase subtilisin/kexin type 7
- domestic cat(101086172) proprotein convertase subtilisin/kexin type 7
- chicken(395455) proprotein convertase subtilisin/kexin type 7
- domestic guinea pig(100728543) proprotein convertase subtilisin/kexin type 7
- sheep(101118814) proprotein convertase subtilisin/kexin type 7
- Domestic Rabbit(100342422) proprotein convertase subtilisin/kexin type 7
- dog(479423) proprotein convertase subtilisin/kexin type 7
- cow(515398) proprotein convertase subtilisin/kexin type 7
- Horse(100062727) proprotein convertase subtilisin/kexin type 7
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Antibodies
货号
说明
物种反应性
应用
Anti-PCSK7 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot