PCDHB11
protocadherin beta 11
ME2, PCDH-BETA11
Human PCDHB11 (56125), Mouse Pcdhb11 (93882), Rat Pcdhb11 (291648), cow PCDHB11 (515336), dog PCDHB11 (487176), sheep PCDHB11 (101102062)
- Human(56125) Summary: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
- Mouse(93882) protocadherin beta 11
- Rat(291648) protocadherin beta 11
- cow(515336) protocadherin beta 11
- dog(487176) protocadherin beta 11
- sheep(101102062) protocadherin beta 11
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Antibodies
Anti-PCDHB11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-PCDHB11 antibody produced in mouse, clone 4F11, purified immunoglobulin, buffered aqueous solution,
human
ELISA