ORC2
origin recognition complex, subunit 2
别名:
ORC2L
物种:
Human ORC2 (4999), Mouse Orc2 (18393), Rat Orc2 (301430), fruit fly Orc2 (41703), Thale Cress ORC2 (818332), domestic guinea pig Orc2 (100718829), naked mole-rat Orc2 (101717321), sheep ORC2 (101106146), Domestic Rabbit ORC2 (100349658), cow ORC2 (511281) ...展开
UniProtKB ID:
基因ID:
- Human(4999) Summary: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]
- Mouse(18393) origin recognition complex, subunit 2
- Rat(301430) origin recognition complex, subunit 2
- fruit fly(41703) Origin recognition complex subunit 2
- Thale Cress(818332) origin recognition complex subunit 2
- domestic guinea pig(100718829) origin recognition complex, subunit 2
- naked mole-rat(101717321) origin recognition complex, subunit 2
- sheep(101106146) origin recognition complex, subunit 2
- Domestic Rabbit(100349658) origin recognition complex, subunit 2
- cow(511281) origin recognition complex, subunit 2
- dog(478868) origin recognition complex, subunit 2
- domestic cat(101085739) origin recognition complex, subunit 2
- Horse(100067880) origin recognition complex, subunit 2
- chicken(424077) origin recognition complex, subunit 2
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Antibodies
货号
说明
物种反应性
应用
Anti-ORC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Rabbit anti-ORC2 Antibody, Affinity Purified, ,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
抗-ORC2抗体（克隆3G6）, clone 3G6, Upstate®, from rat,
物种反应性
human
应用
immunoprecipitation (IP)
western blot
western blot
esiRNA
货号
说明
物种