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Merck
CN

OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

别名:
ARHGEF30, UNC89
物种:
UniProtKB ID:
基因ID:
  • Human(84033) Summary: The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(380698) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • Rat(338458) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • sheep(101121853) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • naked mole-rat(101701039) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • Zebrafish(445358) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • chicken(420395) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • dog(482206) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • domestic cat(101101539) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • cow(537193) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • domestic guinea pig(100727808) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

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Antibodies

货号
说明
物种反应性
应用
Anti-Obscurin Antibody, clone 5H10A, clone 5H10A, from mouse,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-OBSCN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-OBSCN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-C1ORF145 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human OBSCN (1),
物种
human
MISSION® esiRNA, targeting human OBSCN (2),
物种
human