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Merck
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NANS

N-acetylneuraminic acid synthase

别名:
SAS
物种:
UniProtKB ID:
基因ID:
  • Human(54187) Summary: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]
  • Mouse(94181) N-acetylneuraminic acid synthase (sialic acid synthase)
  • Rat(298071) N-acetylneuraminic acid synthase
  • cow(540602) N-acetylneuraminic acid synthase
  • Horse(100064126) N-acetylneuraminic acid synthase
  • domestic cat(101092303) N-acetylneuraminic acid synthase
  • dog(481624) N-acetylneuraminic acid synthase
  • sheep(101104048) N-acetylneuraminic acid synthase
  • domestic guinea pig(100716456) N-acetylneuraminic acid synthase
  • chicken(427283) N-acetylneuraminic acid synthase
  • Domestic Rabbit(100356934) N-acetylneuraminic acid synthase
  • Zebrafish(322780) N-acetylneuraminic acid synthase
  • naked mole-rat(101721582) N-acetylneuraminic acid synthase

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Antibodies

货号
说明
物种反应性
应用
Anti-NANS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-NANS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-NANS antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human NANS,
物种
human
MISSION® esiRNA, targeting mouse Nans,
物种
mouse