跳转至内容
Merck
CN

MS4A2

membrane-spanning 4-domains, subfamily A, member 2

别名:
APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1
物种:
UniProtKB ID:
基因ID:
  • Human(2206) Summary: The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012]
  • Mouse(14126) membrane-spanning 4-domains, subfamily A, member 2
  • Rat(25316) membrane-spanning 4-domains, subfamily A, member 2
  • domestic guinea pig(100715296) membrane-spanning 4-domains, subfamily A, member 2
  • sheep(443203) membrane-spanning 4-domains, subfamily A, member 2
  • naked mole-rat(101703025) membrane-spanning 4-domains, subfamily A, member 2
  • domestic cat(101101505) membrane-spanning 4-domains, subfamily A, member 2
  • dog(403799) membrane-spanning 4-domains, subfamily A, member 2
  • cow(531987) membrane-spanning 4-domains, subfamily A, member 2
  • Horse(100033954) membrane-spanning 4-domains, subfamily A, member 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-MS4A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-MS4A2 antibody produced in mouse, clone 3B1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-MS4A2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MS4A2,
物种
human