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Merck
CN

IPO5

importin 5

别名:
IMB3, KPNB3, Pse1, RANBP5, imp5
物种:
UniProtKB ID:
基因ID:
  • Human(3843) Summary: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008]
  • Mouse(70572) importin 5
  • Rat(306182) importin 5
  • domestic guinea pig(100714433) importin 5
  • cow(508273) importin 5
  • sheep(101109716) importin 5
  • dog(485528) importin 5
  • Horse(100060424) importin 5
  • domestic cat(101097780) importin 5
  • naked mole-rat(101718849) importin 5
  • chicken(418783) importin 5

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Antibodies

货号
说明
物种反应性
应用
Anti-IPO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Importin 5 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-IPO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Importin 5 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
immunoprecipitation (IP)

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ipo5,
物种
mouse
MISSION® esiRNA, targeting human IPO5,
物种
human