HLA-DRA
major histocompatibility complex, class II, DR alpha
HLA-DRA1, MLRW
- Human(3122) Summary: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]
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Antibodies
单克隆抗 HLA-DR 小鼠抗, clone L243, purified immunoglobulin, buffered aqueous solution,
dog, human, nonhuman primates
FUNC
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HLA-DRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
Monoclonal Anti-HLA-DR-DP-FITC antibody produced in mouse, clone MEM-136, purified immunoglobulin, buffered aqueous solution,
human
flow cytometry
Monoclonal Anti-HLA-DR antibody produced in mouse, clone MEM-12, purified immunoglobulin, buffered aqueous solution,
human
flow cytometry
Monoclonal Anti-HLA-DR-DP antibody produced in mouse, clone HL-38, purified immunoglobulin, buffered aqueous solution,
human
flow cytometry