FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
别名:
CD174, FT3B, FucT-III, LE, Les
物种:
Human FUT3 (2525), Thale Cress FUT3 (843783), sheep FUT3 (101108745), naked mole-rat Fut3 (101727627)
UniProtKB ID:
基因ID:
- Human(2525) Summary: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
- Thale Cress(843783) fucosyltransferase 3
- sheep(101108745) fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
- naked mole-rat(101727627) fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
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ELISA
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Antibodies
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说明
物种反应性
应用
Anti-FucT-III Antibody, from rabbit, purified by affinity chromatography,
物种反应性
chimpanzee, human
应用
western blot
Anti-FUT3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
esiRNA
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