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Merck
CN

F7

coagulation factor VII (serum prothrombin conversion accelerator)

别名:
SPCA
物种:
UniProtKB ID:
基因ID:
  • Human(2155) Summary: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(14068) coagulation factor VII
  • Rat(260320) coagulation factor VII (serum prothrombin conversion accelerator)
  • naked mole-rat(101706917) coagulation factor VII (serum prothrombin conversion accelerator)
  • domestic guinea pig(100727155) coagulation factor VII (serum prothrombin conversion accelerator)
  • fruit fly(5657732) f7
  • Zebrafish(114423) coagulation factor VII
  • chicken(395086) coagulation factor VII (serum prothrombin conversion accelerator)
  • dog(607661) coagulation factor VII (serum prothrombin conversion accelerator)
  • domestic cat(101090581) coagulation factor VII (serum prothrombin conversion accelerator)
  • cow(617960) coagulation factor VII (serum prothrombin conversion accelerator)
  • sheep(101118369) coagulation factor VII (serum prothrombin conversion accelerator)
  • Domestic Rabbit(100009399) coagulation factor VII (serum prothrombin conversion accelerator)

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ELISA

货号
说明
物种
Human Coagulation Factor VII ELISA Kit, for cell culture supernatants, plasma, and serum samples,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-因子VII抗体,小鼠单克隆, clone HVII-1, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
western blot
Anti-Coagulation factor VIIa, from rabbit, purified by affinity chromatography,
物种反应性
human, primate
应用
immunocytochemistry
immunofluorescence

western blot
Anti-FA7 (light chain, Cleaved-Arg212) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-F7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
proximity ligation assay
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human F7,
物种
human
MISSION® esiRNA, targeting mouse F7,
物种
mouse