DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
别名:
156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9
物种:
Human DAG1 (1605), Mouse Dag1 (13138), Rat Dag1 (114489), domestic cat DAG1 (100174781), sheep DAG1 (101103515), Horse DAG1 (100053150), Domestic Rabbit DAG1 (100009278), domestic guinea pig Dag1 (100734382), cow DAG1 (281439), naked mole-rat Dag1 (101714190) ...展开
UniProtKB ID:
基因ID:
- Human(1605) Summary: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010]
- Mouse(13138) dystroglycan 1
- Rat(114489) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- domestic cat(100174781) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- sheep(101103515) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Horse(100053150) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Domestic Rabbit(100009278) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- domestic guinea pig(100734382) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- cow(281439) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- naked mole-rat(101714190) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- chicken(100049058) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Zebrafish(286829) dystroglycan 1
- Thale Cress(825358) Dof zinc finger protein DOF3.7
- dog(476623) dystroglycan 1 (dystrophin-associated glycoprotein 1)
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Antibodies
货号
说明
物种反应性
应用
抗-α-肌营养不良蛋白聚糖抗体，克隆VIA4-1, culture supernatant, clone VIA4-1, Upstate®,
物种反应性
canine, guinea pig, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Anti-TROP2 Antibody, clone TrMab-29, ,
物种反应性
human
应用
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-α-肌营养不良蛋白聚糖抗体，克隆IIH6C4, ascites fluid, clone IIH6C4, Upstate®,
物种反应性
canine, guinea pig, human, mouse, rabbit, rat
应用
immunofluorescence
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anti-α-Dystroglycan Antibody, clone VIA4-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
canine, guinea pig, human, mouse, rabbit, rat
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot