DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
别名:
DOC-2, DOC2
物种:
Human DAB2 (1601), Mouse Dab2 (13132), Rat Dab2 (79128), dog DAB2 (479353), Zebrafish dab2 (404040), chicken DAB2 (427449), sheep DAB2 (101104604), naked mole-rat Dab2 (101725399), cow DAB2 (509221), Horse DAB2 (100066655) ...展开
UniProtKB ID:
基因ID:
- Human(1601) Summary: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(13132) disabled 2, mitogen-responsive phosphoprotein
- Rat(79128) disabled 2, mitogen-responsive phosphoprotein
- dog(479353) disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- Zebrafish(404040) disabled homolog 2 (Drosophila)
- chicken(427449) disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- sheep(101104604) disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- naked mole-rat(101725399) Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
- cow(509221) disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- Horse(100066655) disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- domestic guinea pig(100734816) Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
- domestic cat(101096539) disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
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Antibodies
货号
说明
物种反应性
应用
Anti-DAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-DAB2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Monoclonal Anti-DAB2 antibody produced in mouse, clone 3D6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-DAB2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, canine, human, rat
应用
ELISA
western blot
western blot
Monoclonal Anti-DAB2, (C-terminal) antibody produced in mouse, clone 1C8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
esiRNA
货号
说明
物种