跳转至内容
Merck
CN

COPS5

COP9 signalosome subunit 5

别名:
CSN5, JAB1, MOV-34, SGN5
物种:
UniProtKB ID:
基因ID:
  • Human(10987) Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
  • Mouse(26754) COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)
  • Rat(312916) COP9 signalosome subunit 5
  • domestic cat(101092084) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • Zebrafish(393698) COP9 constitutive photomorphogenic homolog subunit 5
  • chicken(426579) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • domestic guinea pig(100716886) COP9 signalosome subunit 5
  • naked mole-rat(101710038) COP9 signalosome subunit 5
  • Horse(100051846) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • cow(507179) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • sheep(101101995) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • dog(477901) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-COPS5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-COPS5 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
western blot
Monoclonal Anti-COPS5 antibody produced in mouse, ,
物种反应性
drosophila, human, mouse, rat
应用
immunocytochemistry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-JAB1/CSN5/COPS5 antibody produced in rabbit, ,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-COPS5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human COPS5,
物种
human