跳转至内容
Merck
CN

CNTNAP2

contactin associated protein-like 2

别名:
AUTS15, CASPR2, CDFE, NRXN4, PTHSL1
物种:
UniProtKB ID:
基因ID:
  • Human(26047) Summary: This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.[provided by RefSeq, Mar 2010]
  • Mouse(66797) contactin associated protein-like 2
  • Rat(500105) contactin associated protein-like 2
  • Horse(100060296) contactin associated protein-like 2
  • Domestic Rabbit(100354524) contactin associated protein-like 2
  • chicken(768456) contactin associated protein-like 2
  • sheep(101106322) contactin associated protein-like 2
  • dog(100687859) contactin associated protein-like 2
  • domestic cat(101086795) contactin associated protein-like 2
  • cow(100337375) contactin associated protein-like 2
  • cow(516395) contactin associated protein-like 2
  • domestic guinea pig(100717858) contactin associated protein-like 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
人Caspr2 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-CNTNAP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
抗Caspr2抗体,胞外域, serum, from rabbit,
物种反应性
human, mouse
应用
immunocytochemistry
western blot
Anti-CNTNAP2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-Caspr2 Antibody, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot
Anti-CNTNAP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CNTNAP2,
物种
human
MISSION® esiRNA, targeting mouse Cntnap2,
物种
mouse