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Merck
CN

CHRM1

cholinergic receptor, muscarinic 1

别名:
HM1, M1, M1R
物种:
Human CHRM1 (1128), Mouse Chrm1 (12669), Rat Chrm1 (25229), domestic guinea pig Chrm1 (100728041), domestic cat CHRM1 (493664), domestic cat CHRM1 (101093801), dog CHRM1 (483776), sheep CHRM1 (101117029), cow CHRM1 (281684), Horse CHRM1 (100064117)
UniProtKB ID:
P11229
基因ID:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1

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Small Molecule - Agonist

货号
说明
物种
P0597
毛果芸香碱 硝酸酯, meets USP testing specifications,
物种
human
A2251
乙酰基-β-氯化甲基胆碱, ≥98% (TLC), powder,
物种
human
O100
氧化震颤素M, solid,
物种
human
C4382
卡巴胆碱, ≥98% (titration), crystalline,
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
197602
奎宁环, 97%,
物种
rat
E5406
爱普杷嗪 盐酸盐, ≥98% (HPLC), powder,
物种
human
P7412
哌仑西平 二盐酸盐, ≥98% (TLC), powder,
物种
human
1687006
苯海索 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
P3794
Procyclidine hydrochloride, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
HPA014101
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
AB5164
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot
SAB4500244
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
M9808
抗 毒蕈碱乙酰胆碱受体 (M 1 ) 兔抗, affinity isolated antibody, lyophilized powder,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
A8404
盐酸阿米替林 盐酸盐, ≥98% (TLC), powder,
物种
human
D4526
多塞平 盐酸盐, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
物种
human
H1512
氟哌啶醇, powder,
物种
human, rat
C6305
氯氮平标准液, ,
物种
human, rat

Proteins

货号
说明
物种
HTS044RTA
Ready-to-Assay M1 Acetylcholine (Muscarinic) Family Receptor Frozen Cells, ,
物种
human
HTS044M
ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
物种
human

esiRNA

货号
说明
物种
EHU009821
MISSION® esiRNA, targeting human CHRM1,
物种
human