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Merck
CN

PHR1470

Supelco

东莨菪碱氢溴酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
东莨菪碱 氢溴酸盐
经验公式(希尔记法):
C17H21NO4 · HBr · 3H2O
CAS号:
分子量:
438.31
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to BP 199
traceable to Ph. Eur. H1500000
traceable to USP 1610001

API类

scopolamine, hyoscine

CofA

current certificate can be downloaded

包装

pkg of 500 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

InChI

1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1

InChI key

WTGQALLALWYDJH-MOUKNHLCSA-N

基因信息

human ... CHRM1(1128)

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
Scopolamine Hydrobromide is the hydrobromide salt of scopolamine, naturally found in belladonna plant. It belongs to the group of cycloplegic drugs, which produces cycloplegia. Its mode of action involves inhibiting the action of acetylcholine at muscarinic receptors in the ciliary muscle.

应用

Scopolamine Hydrobromide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB7821 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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访问文档库

Dictionary of Optometry and Visual Science, 590(2), 341-353 (2014)
Topical Drug Bioavailability, Bioequivalence, and Penetration, 590(2), 341-353 (1993)
LC determination of atropine sulfate and scopolamine hydrobromide in pharmaceuticals.
Ceyhan T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 399-406 (2001)
Comparison of isotachophoresis, capillary zone electrophoresis and high-performance liquid chromatography for the determination of salbutamol, terbutaline sulphate and fenoterol hydrobromide in pharmaceutical dosage forms
Ackermans TM, et al.
Journal of Chromatography A, 590(2), 341-353 (1992)

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