跳转至内容
Merck
CN

CFL1

cofilin 1 (non-muscle)

别名:
CFL
物种:
UniProtKB ID:
基因ID:
  • Human(1072) Summary: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
  • Mouse(12631) cofilin 1, non-muscle
  • Rat(29271) cofilin 1, non-muscle
  • sheep(494432) cofilin 1 (non-muscle)
  • dog(476022) cofilin 1 (non-muscle)
  • Zebrafish(406738) cofilin 1 (non-muscle)
  • cow(534553) cofilin 1 (non-muscle)
  • naked mole-rat(101713836) cofilin 1 (non-muscle)
  • domestic cat(101100251) cofilin 1 (non-muscle)
  • domestic guinea pig(100732287) cofilin 1 (non-muscle)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-Cfl1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-CFL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Monoclonal Anti-Cofilin 1 antibody produced in mouse, clone GT567, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-phospho Cofilin-1 Antibody (Ser3), from rabbit, purified by affinity chromatography,
物种反应性
bovine, human, mouse, porcine, rat
应用
inhibition assay
western blot
抗-丝切蛋白-1抗体, from rabbit, purified by affinity chromatography,
物种反应性
bovine, human, mouse, porcine, rat
应用
immunoprecipitation (IP)
western blot

Proteins

货号
说明
物种
活性Cofilin 1 人, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物种
human