CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
别名:
EHT, MTGR1, ZMYND3, p85
物种:
Human CBFA2T2 (9139), Mouse Cbfa2t2 (12396), Rat Cbfa2t2 (296293), domestic cat CBFA2T2 (101090759), Zebrafish cbfa2t2 (100151413), domestic guinea pig Cbfa2t2 (100729254), naked mole-rat Cbfa2t2 (101719942), chicken CBFA2T2 (419155), dog CBFA2T2 (477196), cow CBFA2T2 (527740) ...展开
UniProtKB ID:
基因ID:
- Human(9139) Summary: In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008]
- Mouse(12396) core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
- Rat(296293) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- domestic cat(101090759) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- Zebrafish(100151413) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- domestic guinea pig(100729254) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- naked mole-rat(101719942) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- chicken(419155) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- dog(477196) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- cow(527740) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- Domestic Rabbit(100357211) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- sheep(101110436) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
- Horse(100069109) core-binding factor, runt domain, alpha subunit 2; translocated to, 2
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Antibodies
货号
说明
物种反应性
应用
Anti-CBFA2T2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-CBFA2T2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Monoclonal Anti-CBFA2T2 antibody produced in mouse, clone 2C10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CBFA2T2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-CBFA2T2 antibody produced in mouse, clone 3A2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
esiRNA
货号
说明
物种