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Merck
CN

BCL2A1

BCL2-related protein A1

别名:
ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1
物种:
UniProtKB ID:
基因ID:
  • Human(597) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(170929) BCL2-related protein A1
  • cow(282151) BCL2-related protein A1
  • chicken(395673) BCL2-related protein A1
  • dog(488770) BCL2-related protein A1
  • naked mole-rat(101702935) BCL2-related protein A1
  • domestic cat(768283) BCL2-related protein A1
  • sheep(101114560) BCL2-related protein A1
  • domestic cat(101086480) BCL2-related protein A1
  • domestic guinea pig(100732983) BCL2-related protein A1

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Antibodies

货号
说明
物种反应性
应用
Anti-BCL2A1 Antibody/BFL-1, serum, from rabbit,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-BCL2A1/BFL-1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
camelidae, bat, bovine, chimpanzee, human
应用
immunohistochemistry
western blot
Anti-BFL-1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

western blot
Anti-BFL-1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-BFL-1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human BCL2A1,
物种
human