APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
别名:
APE, APE1, APEN, APEX, APX, HAP1, REF1
物种:
Human APEX1 (328), Mouse Apex1 (11792), Rat Apex1 (79116), cow APEX1 (281630), Goat APEX1 (100860967), chicken APEX1 (100431102), dog APEX1 (482558), domestic cat APEX1 (101101318), Zebrafish apex1 (406730), domestic guinea pig Apex1 (100719062) ...展开
UniProtKB ID:
基因ID:
- Human(328) Summary: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(11792) apurinic/apyrimidinic endonuclease 1
- Rat(79116) APEX nuclease (multifunctional DNA repair enzyme) 1
- cow(281630) APEX nuclease (multifunctional DNA repair enzyme) 1
- Goat(100860967) APEX nuclease (multifunctional DNA repair enzyme) 1
- chicken(100431102) APEX nuclease (multifunctional DNA repair enzyme) 1
- dog(482558) APEX nuclease (multifunctional DNA repair enzyme) 1
- domestic cat(101101318) APEX nuclease (multifunctional DNA repair enzyme) 1
- Zebrafish(406730) APEX nuclease (multifunctional DNA repair enzyme) 1
- domestic guinea pig(100719062) APEX nuclease (multifunctional DNA repair enzyme) 1
- naked mole-rat(101709711) APEX nuclease (multifunctional DNA repair enzyme) 1
- sheep(101115462) APEX nuclease (multifunctional DNA repair enzyme) 1
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Antibodies
货号
说明
物种反应性
应用
抗-APEX1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-APEX1 antibody produced in mouse, clone 4D1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-APEX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-APEX1 antibody produced in mouse, clone 3E12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
Anti-APEX1/APE1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot