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Merck
CN

AGTR1

angiotensin II receptor, type 1

别名:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
物种:
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), Domestic Rabbit AGTR1 (100009164), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), dog AGTR1 (403836), chicken AGTR1 (396065), cow AGTR1 (281607), domestic cat AGTR1 (101082936)
UniProtKB ID:
P30556, Q13725
基因ID:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Antagonist

货号
说明
物种
PHR1855
替米沙坦, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
PHR1602
氯沙坦钾, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
PHR1315
缬沙坦, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
SML0142
缬沙坦, ≥98% (HPLC),
物种
human
1370462
氯沙坦钾, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
AB15552
抗-AT1受体抗体, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
SAB3500209
抗 AGTR1 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
ZRB2442
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, human, mouse, rat
应用
affinity binding assay
immunocytochemistry
western blot
SAB2100073
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
应用
western blot
SAB5702971
Anti-AT1R/AGTR1 Antibody, clone 8W6G0, Rabbit Monoclonal, ,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
C4042
卡托普利, ≥98% (HPLC), powder,
物种
human, rat
547905
2,2′:5′,2′′:5′′,2′′′-四噻吩, 96%,
物种
human, rat, mouse

Proteins

货号
说明
物种
HTS064M
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
物种
human

esiRNA

货号
说明
物种
EHU090121
MISSION® esiRNA, targeting human AGTR1,
物种
human