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Merck
CN

ACTL6A

actin-like 6A

别名:
ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K
物种:
UniProtKB ID:
基因ID:
  • Human(86) Summary: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(56456) actin-like 6A
  • Rat(361925) actin-like 6A
  • cow(100125416) actin-like 6A
  • dog(478637) actin-like 6A
  • domestic cat(101091095) actin-like 6A
  • Horse(100065792) actin-like 6A
  • Domestic Rabbit(100338581) actin-like 6A
  • sheep(101108709) actin-like 6A
  • Zebrafish(192313) actin-like 6A
  • naked mole-rat(101716407) actin-like 6A
  • domestic guinea pig(100725106) actin-like 6A
  • chicken(424975) actin-like 6A

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Antibodies

货号
说明
物种反应性
应用
Anti-ACTL6A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
Anti-ACTL6A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
Monoclonal Anti-ACTL6A antibody produced in mouse, clone 3E4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-ACTL6A Antibody, clone 5U6J8, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ACTL6A,
物种
human