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T2663

Sigma-Aldrich

Trizma® hydrochloride solution

1 M, BioReagent

Synonym(s):

Tris hydrochloride solution

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5 MG
CN¥2,969.89
25 MG
CN¥7,779.18

CN¥2,969.89

Available to ship onApril 23, 2025Details

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5 MG
CN¥2,969.89
25 MG
CN¥7,779.18

About This Item

MDL number:
MFCD00012590
UNSPSC Code:
12161700
PubChem Substance ID:
24900064
NACRES:
NA.25

CN¥2,969.89

Available to ship onApril 23, 2025Details

Request a Bulk Order

grade

Molecular Biology

Quality Level

200

sterility

0.2 μm filtered

product line

BioReagent

form

solution

concentration

1 M

impurities

DNase, RNase, NICKase and protease, none detected

pH

7.35-7.45

SMILES string

Cl.NC(CO)(CO)CO

InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

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Show Differences

1 of 4

This Item
SML1780SML2384SML1276
BAY-876 ≥98% (HPLC)

SML1774

BAY-876

BAY-588 ≥98% (HPLC)

SML1780

BAY-588

BAY 87-2243 ≥98% (HPLC)

SML2384

BAY 87-2243

BAZ2-ICR ≥98% (HPLC)

SML1276

BAZ2-ICR

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 25 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige

General description

Trizma® hydrochloride solution is a useful biological buffer.

Application

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per degree C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Trizma® hydrochloride along with Trizma-base is used to prepare buffer solutions of pH 7.35.[1] It was used to prepare the triton extract.[2] It may be used in the analysis of protease activity, isolated from the Bacillus stearothermophilus and Bacillus subtilis.[3] It may be employed as buffer for the restriction fragment analysis of genomic DNA isolated from the enterococcal isolates and Escherichia coli.[4]

Other Notes

Prepared with pH-adjusted Biotechnology Performance Certified Trizma Base in 18 megohm water and 0.2 μm filtered.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

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    0000251429
    0000251429
    0000423330
    0000423330
    SLCR1843

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    Reconstitution and purification of the D-glucose transporter from human erythrocytes.
    M Kasahara et al.
    The Journal of biological chemistry, 252(20), 7384-7390 (1977-10-25)
    El-Refaie Kenawy et al.
    Journal of controlled release : official journal of the Controlled Release Society, 81(1-2), 57-64 (2002-05-07)
    Electrospun fiber mats are explored as drug delivery vehicles using tetracycline hydrochloride as a model drug. The mats were made either from poly(lactic acid) (PLA), poly(ethylene-co-vinyl acetate) (PEVA), or from a 50:50 blend of the two. The fibers were electrospun
    B E Murray et al.
    Journal of clinical microbiology, 28(9), 2059-2063 (1990-09-01)
    Epidemiologic evaluation of enterococci has been limited by the lack of a simple and effective method for comparing strains. In this study, we have compared chromosomal restriction endonuclease digestion patterns of 27 isolates of Enterococcus faecalis from three different locations
    M Fujii et al.
    Journal of bacteriology, 154(2), 831-837 (1983-05-01)
    The structural gene for a thermostable protease from Bacillus stearothermophilus was cloned in plasmid pTB90. It is expressed in both B. stearothermophilus and Bacillus subtilis. B. stearothermophilus carrying the recombinant plasmid produced about 15-fold more protease (310 U/mg of cell
    Pengyi Yang et al.
    Cell systems, 8(5), 427-445 (2019-05-13)
    Pluripotency is highly dynamic and progresses through a continuum of pluripotent stem cell states. The two states that bookend the pluripotency continuum, naive and primed, are well characterized, but our understanding of the intermediate states and transitions between them remains
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