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N0761

Sigma-Aldrich

Nicotinic acid

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

Synonym(s):

3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3

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1 EA
CN¥7,908.02

CN¥7,908.02

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1 EA
CN¥7,908.02

About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
59-67-6
Molecular Weight:
123.11
Beilstein:
109591
EC Number:
200-441-0
MDL number:
MFCD00006391
UNSPSC Code:
12352207
PubChem Substance ID:
24897443
NACRES:
NA.71

CN¥7,908.02

Please contact Customer Service for Availability
Request a Bulk Order

product line

BioReagent

Quality Level

200

Assay

≥98%

form

powder

mol wt

Mw 123.11 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

color

white to off-white

pH

3.4 (20 °C, 10 g/L)

mp

236-239 °C (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, colorless to very faintly yellow

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P2088

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form

essentially salt-free, lyophilized powder

form

essentially salt-free, lyophilized powder

form

essentially salt-free, lyophilized powder

form

essentially salt-free, lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

mol wt

~44 kDa

mol wt

~44 kDa

mol wt

~44 kDa

mol wt

~44 kDa

solubility

0.1 M phosphate buffer: soluble (pH 6.0), H2O: soluble

solubility

0.1 M phosphate buffer: soluble 10 mg/mL, clear, orange to red (pH 6.0)

solubility

0.1 M phosphate buffer: soluble (pH 6.0), H2O: soluble

solubility

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

300

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

379.4 °F - closed cup

Flash Point(C)

193 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000392792
    0000368371
    0000350397
    0000342104
    0000328013

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    Sorin Tunaru et al.
    Nature medicine, 9(3), 352-355 (2003-02-04)
    Nicotinic acid (niacin), a vitamin of the B complex, has been used for almost 50 years as a lipid-lowering drug. The pharmacological effect of nicotinic acid requires doses that are much higher than those provided by a normal diet. Its
    John R Guyton et al.
    Journal of the American College of Cardiology, 62(17), 1580-1584 (2013-08-07)
    This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial. During a
    Koon K Teo et al.
    Stroke, 44(10), 2688-2693 (2013-07-25)
    In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental
    Paul M Lavigne et al.
    Journal of the American College of Cardiology, 61(4), 440-446 (2012-12-26)
    This study sought to assess the efficacy of niacin for reducing cardiovascular disease (CVD) events, as indicated by the aggregate body of clinical trial evidence including data from the recently published AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High
    Martina Lukasova et al.
    Trends in pharmacological sciences, 32(12), 700-707 (2011-09-29)
    Nicotinic acid (niacin) has been used for decades to prevent and treat atherosclerosis. The well-documented antiatherogenic activity is believed to result from its antidyslipidemic effects, which are accompanied by unwanted effects, especially a flush. There has been renewed interest in
    View All Related Papers

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