F8758
Folic acid
BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%
Synonym(s):
Pterylmonoglutamic acid, PteGlu, Pteroyl-L-glutamic acid, Vitamin M
About This Item
Recommended Products
biological source
synthetic
Quality Level
product line
BioReagent
Assay
≥97%
form
powder
mol wt
Mw 441.40 g/mol
technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable
color
dark yellow
solubility
1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange
storage temp.
room temp
SMILES string
NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
InChI
1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChI key
OVBPIULPVIDEAO-LBPRGKRZSA-N
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General description
Application
- to study the role of vitamins and amino acids on hybridoma growth and monoclonal antibody production
- in cells and treatments
- in perforin gene targeting using the CRISPR/Cas gene editing approach
Biochem/physiol Actions
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Personal Protective Equipment
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the solubility of folic acid (Product No. F8758)?
Product No. F8758 is soluble in 1 M NaOH (50 mg/mL). The free acid is only slightly soluble in water (0.01 mg/mL at 0 °C), and is insoluble in aqueous solutions below pH 5. It is soluble in sodium bicarbonate or sodium hydroxide solutions.
What is the stability of folic acid (Product No. F8758) once in solution?
This product is photolabile and is inactivated by UV light. Alkaline solutions are reasonably stable in the dark, but heating will destroy both alkaline and acidic solutions.
Is Product No. F8758, Folic Acid, tested for endotoxins?
No, Product No. F8758 has not been tested for endotoxins. This product has, however, been tested for use in mammalian cell culture and insect cell culture.
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Articles
Explore folic acid importance in serum-free eukaryotic cell cultures, including CHO cells, and its role in media supplementation.
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