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C8890

Sigma-Aldrich

4-Chloro-1-naphthol

horseradish peroxidase substrate, fluorogenic, ≥98% (GC), crystalline

Synonym(s):

4-chloronaphthalen-1-ol

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2.5 G
CN¥753.33
5 G
CN¥882.81
25 G
CN¥3,158.37
100 G
CN¥10,143.02

CN¥753.33

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2.5 G
CN¥753.33
5 G
CN¥882.81
25 G
CN¥3,158.37
100 G
CN¥10,143.02

About This Item

Linear Formula:
ClC10H6OH
CAS Number:
604-44-4
Molecular Weight:
178.61
Beilstein:
509750
EC Number:
210-068-5
MDL number:
MFCD00003974
UNSPSC Code:
12352204
PubChem Substance ID:
57654054
NACRES:
NA.83

CN¥753.33

Please contact Customer Service for Availability

Product Name

4-Chloro-1-naphthol, crystalline

Assay

≥98% (GC)

form

crystalline

mp

118-121 °C (lit.)

solubility

acetone: 50 mg/mL, clear, colorless to very faintly brown

storage temp.

−20°C

SMILES string

Oc1ccc(Cl)c2ccccc12

InChI

1S/C10H7ClO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H

InChI key

LVSPDZAGCBEQAV-UHFFFAOYSA-N

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Show Differences

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This Item
C6788A8003M2514
4-Chloro-1-naphthol crystalline

C8890

4-Chloro-1-naphthol

4-Chloro-1-naphthol tablet

C6788

4-Chloro-1-naphthol

Allopurinol xanthine oxidase inhibitor

A8003

Allopurinol

4-Methylumbelliferyl heptanoate ≥95% (GC)

M2514

4-Methylumbelliferyl heptanoate

solubility

acetone: 50 mg/mL, clear, colorless to very faintly brown

solubility

methanol: 10 mL, clear, colorless

solubility

1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

crystalline

form

tablet

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

mp

118-121 °C (lit.)

mp

118-121 °C (lit.)

mp

>300 °C (lit.)

mp

41-42 °C (lit.)

Application

4-Chloro-1-naphthol has been used to visualize protein bands in western blotting.[1] It has also been used in staining polyvinylidene fluoride (PVDF) membrane by Nakane method.[2][1]

Biochem/physiol Actions

4-Chloro-1-naphthol serves as a substrate for horseradish peroxidase.[3]

Substrates

Chromogenic peroxidase substrate useful in enzyme-linked detection procedures.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCW5673
    MKCW6751
    MKCM2556
    MKCQ6135
    MKCQ0017

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    Find documentation for the products that you have recently purchased in the Document Library.

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    Endothelial microparticles induce formation of platelet aggregates via a von Willebrand factor/ristocetin dependent pathway, rendering them resistant to dissociation
    JIMENEZ JJ, et al.
    Journal of Thrombosis and Haemostasis, 3(6), 1301-1308 (2005)
    Limited proteolysis of fibrinogen by fibrinogenase from Echis multisquamatis venom
    Chernyshenko VO
    The Protein Journal, 34(2), 130-134 (2015)
    D J Litman et al.
    Clinical chemistry, 29(9), 1598-1603 (1983-09-01)
    We describe an internally referenced immunochemical test-strip for use in the rapid detection of morphine. The method is based on the "enzyme-channelling" immunoassay technique, and a glucose oxidase-horseradish peroxidase enzyme pair is used to immunospecifically generate an insoluble, colored reaction
    A Domingo et al.
    Analytical biochemistry, 182(1), 176-181 (1989-10-01)
    As described in this article, visualization and/or photography under uv light of 4-chloro-1-naphthol-developed, peroxidase-marked immunoblots allows an increase in sensitivity of more than 100 times over the apparent staining results observable under normal visible white light. This increase in sensitivity
    R Kobayashi et al.
    Analytical biochemistry, 183(1), 9-12 (1989-11-15)
    A method which allows the highly sensitive and simple immunodetection of antigen-antibody complexes on nitrocellulose papers has been developed. The method is a modification of the procedure known as the "Nadi reaction" (oxidative coupling of 1-naphthol and N,N'-dimethyl-p-phenylendiamine) for histochemical
    View All Related Papers

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