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S5016

Sigma-Aldrich

Sucrose

ACS reagent

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Synonym(s):
α-D-Glc-(1→2)-β-D-Fru, α-D-Glucopyranosyl β-D-fructofuranoside, β-D-Fructofuranosyl-α-D-glucopyranoside, D(+)-Saccharose, Sugar
Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
57-50-1
Molecular Weight:
342.30
Beilstein:
90825
EC Number:
200-334-9
MDL number:
MFCD00006626
UNSPSC Code:
12352201
PubChem Substance ID:
24899632
NACRES:
NA.21

biological source

sugar cane

Quality Level

300

grade

ACS reagent

form

powder or crystals

optical activity

[α]25/D +66.3 to +66.8°(lit.)

technique(s)

HPLC: suitable
cryopreservation: suitable
immunohistochemistry: suitable

impurities

≤0.0008 meq/g Titratable acid
≤0.005% Insoluble matter
≤0.05% Invert sugar

ign. residue

≤0.01%

loss

≤0.03% loss on drying, 105°C

color

white

useful pH range

5.5-7.5 (25 °C, 342 g/L)

mp

185-187 °C (lit.)

solubility

soluble 342 g/L at 20 °C (completely)

anion traces

chloride (Cl-): ≤0.005%
sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

application(s)

agriculture
cell analysis
life science and biopharma
metabolomics

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

CZMRCDWAGMRECN-UGDNZRGBSA-N

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General description

Sucrose, a disaccharide consisting of glucose and fructose, serves as an energy source in numerous biological processes. In cell culture, sucrose functions as a cryoprotectant, preserving cell viability during freezing and thawing while also helping to maintain osmotic balance and enhance cell survival. Moreover, sucrose finds utility as a supplement in plant, insect, and bacterial culture media, and it is applied in various enzymatic assays. In biomedical research, it plays a role as an osmolyte, an algal metabolite, a Saccharomyces cerevisiae metabolite, an E. coli metabolite, and a mouse metabolite.

Application

Sucrose has been used
  • in a growth medium to study the molecular and biochemical aspects of plant-pathogen interactions and plant immune responses
  • as a cryoprotectant in a study involving antibiotic-induced changes to the gut microbiota and their effects on neuroimmune interactions

Biochem/physiol Actions

Sucrose serves as a vital energy source, undergoing metabolic conversion to produce adenosine triphosphate (ATP) for cellular functions and cellular respiration. In plant biology, sucrose is central to photosynthesis and acts as a storage carbohydrate in various plant parts. In Cell Biology, it helps maintain osmotic balance in cells, acts as a cryoprotectant in laboratory settings, and participates in biosynthesis, leading to the formation of secondary metabolites.

Features and Benefits

  • Suitable for cell biology and biochemical research
  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Tested for anion and cation traces
  • ACS grade sucrose, sourced from sugar cane

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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S0389

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S5390

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S7903

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S1888

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16104

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84097

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RDD023

Sucrose, anhydrous, free-flowing, Redi-Dri™, ACS reagent

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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OXIDATIVE SIGNAL-INDUCIBLE1 induces immunity by coordinating N-hydroxypipecolic acid, salicylic acid, and camalexin synthesis
Rawat et al.
The New phytologist, 237, 1285-1301 (2023)
Mònica Aguilera et al.
International journal of molecular sciences, 22(15) (2021-08-08)
Interactions between the intestinal microbiota, immune system and nervous system are essential for homeostasis in the gut. Inflammasomes contribute to innate immunity and brain-gut interactions, but their role in microbiota-neuro-immune interactions is not clear. Therefore, we investigated the effect of
Julia B Cordero et al.
The EMBO journal, 33(13), 1474-1491 (2014-05-03)
The non-receptor tyrosine kinase c-Src, hereafter referred to as Src, is overexpressed or activated in multiple human malignancies. There has been much speculation about the functional role of Src in colorectal cancer (CRC), with Src amplification and potential activating mutations
Denise Harrison et al.
Pediatrics, 130(5), 918-925 (2012-10-10)
The use of oral sucrose has been the most extensively studied pain intervention in newborn care to date. More than 150 published studies relating to sweet-taste-induced calming and analgesia in human infants have been identified, of which 100 (65%) include
Rafaela Ribeiro Reis et al.
Plant science : an international journal of experimental plant biology, 221-222, 59-68 (2014-03-25)
Drought is one of the most challenging agricultural issues limiting sustainable sugarcane production and, in some cases, yield losses caused by drought are nearly 50%. DREB proteins play vital regulatory roles in abiotic stress responses in plants. The transcription factor
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