Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
All Photos(2)

Key Documents

View All Documentation

91928

Supelco

2′,4′,6′-Trihydroxyacetophenone monohydrate

≥99.5%

Synonym(s):

2-Acetylphloroglucinol, THAP

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
CN¥1,188.40
5 G
CN¥4,598.42

CN¥1,188.40

Available to ship onApril 14, 2025Details

Request a Bulk Order
All Photos(2)

Select a Size

Change View
1 G
CN¥1,188.40
5 G
CN¥4,598.42

About This Item

Linear Formula:
(HO)3C6H2COCH3·H2O
CAS Number:
249278-28-2
Molecular Weight:
186.16
Beilstein:
9288656
MDL number:
MFCD00149091
UNSPSC Code:
41115716
PubChem Substance ID:
329770099
NACRES:
NA.21

CN¥1,188.40

Available to ship onApril 14, 2025Details

Request a Bulk Order

Quality Level

100

Assay

≥99.5% (HPLC)
≥99.5%

form

solid

analyte chemical class(es)

glycans, oligonucleotides, peptides, proteins

technique(s)

MALDI-MS: suitable

color

light yellow

mp

218-222 °C
219-221 °C (lit.)

cation traces

Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

suitability

in accordance for UV test
suitable for matrix substance for MALDI-MS

SMILES string

O.CC(=O)c1c(O)cc(O)cc1O

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
491527T6460292220
2′,4′,6′-Trihydroxyacetophenone monohydrate ≥99.5%

91928

2′,4′,6′-Trihydroxyacetophenone monohydrate

4′-Chloroacetophenone-2′,3′,5′,6′-d4 98 atom % D

491527

4′-Chloroacetophenone-2′,3′,5′,6′-d4

2′,4′,6′-Trihydroxyacetophenone monohydrate 98%

T64602

2′,4′,6′-Trihydroxyacetophenone monohydrate

2′,4′,6′-Trimethylacetophenone ≥98.0% (GC)

92220

2′,4′,6′-Trimethylacetophenone

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

mp

218-222 °C, 219-221 °C (lit.)

mp

14-18 °C (lit.)

mp

219-221 °C (lit.)

mp

-

form

solid

form

-

form

-

form

liquid

grade

matrix substance for MALDI-MS

grade

-

grade

-

grade

-

analyte chemical class(es)

glycans, oligonucleotides, peptides, proteins

analyte chemical class(es)

-

analyte chemical class(es)

-

analyte chemical class(es)

-

General description

MALDI-MS analyzes require highest purity matrices and reagents, as organic or trace metal contamination causes adverse effects during crystallization, ionization or measurement. Therefore, our portfolio of MALDI matrices and reagents such as 2′,4′,6′-Trihydroxyacetophenone monohydrate are designed to fulfill the demanding requirements of today′s challenging applications.

Application

2′,4′,6′-Trihydroxyacetophenone monohydrate has been used as a matrix for oligosaccharide and glycopeptide analysis using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI/TOF).[1]
Used in MALDI analysis of acidic glycans and glyco­peptides in negative ion mode. Lower limit of detection than 6-aza-2-thiothimidine.[2]

related product

Product No.
Description
Pricing

P2613

ProteoMass™ P14R MALDI-MS Standard, vial of 10 nmol

C8857

ProteoMass™ Cytochrome c MALDI-MS Standard, vial of 10 nmol, (M+H+) 12,361.96 Da by calculation

C8982

α-Cyano-4-hydroxycinnamic acid, suitable for MALDI-TOF MS

A8346

ProteoMass™ ACTH Fragment 18-39 MALDI-MS Standard, vial of 10 nmol, monoisotopic mol wt 2,464.1989 Da

I6154

ProteoMass™ Insulin chain B oxidized MALDI-MS Standard, vial of 10 nmol

I6279

ProteoMass™ Insulin MALDI-MS Standard, vial of 10 nmol, monoisotopic mol wt 5,729.6087 Da

A8471

ProteoMass™ Albumin MALDI-MS Standard, vial of 10 nmol, average mol wt 66,429.09 Da by calculation

A9096

ProteoMass™ Aldolase MALDI-MS Standard, vial of 10 nmol, average mol wt 39,211.28 Da by calculation

A8846

ProteoMass™ Angiotensin II MALDI-MS Standard, vial of 10 nmol

A8971

ProteoMass™ Apomyoglobin MALDI-MS Standard, vial of 10 nmol, (M+H+) 16,952.27 Da by calculation

B4181

ProteoMass™ Bradykinin Fragment 1-7 MALDI-MS Standard, vial of 10 nmol, monoisotopic mol wt 756.3997 Da

MSCAL1

ProteoMass™ Peptide and Protein MALDI-MS Calibration Kit, Peptide and Protein MALDI MS Calibration Standard

MSCAL2

ProteoMass™ Peptide MALDI-MS Calibration Kit, Peptide MALDI MS Calibration Standard

MSCAL3

ProteoMass™ Protein MALDI-MS Calibration Kit, Protein MALDI MS Calibration Standard

56197

3-Hydroxypicolinic acid, ≥99.0% (HPLC)

54793

2-(4-Hydroxyphenylazo)benzoic acid, ≥99.5%

85429

Sinapic acid, ≥99.0% (T)

03565

MALDI validation set polystyrene Mp ~700 - 70 000, certified reference material

37468

2′,6′-Dihydroxyacetophenone, ≥99.5%

87884

trans-2-[3-(4-tert-Butylphenyl)-2-methyl-2-propenylidene]malononitrile, ≥99.0% (HPLC)

60018

Caffeic acid, ≥99.0% (HPLC)

29208

(N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide, ≥98.5%

46278

trans-Ferulic acid, ≥99.0% (HPLC)

85707

2,5-Dihydroxybenzoic acid, >99.0% (HPLC)

70990

α-Cyano-4-hydroxycinnamic acid, ≥99.0% (HPLC)

N3786

α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens, Proteomics Grade, suitable for MALDI-TOF MS

39468

α-Cyano-4-hydroxycinnamic acid, Ultra pure

39319

2,5-Dihydroxybenzoic acid, ≥99.5% (HPLC), Ultra pure

49508

Sinapic acid, ≥99.5%, Ultra pure

50862

Super-DHB, suitable for matrix substance for MALDI-MS, ≥99.0%

02241

2′,3′-Dideoxycytidine 5′-triphosphate sodium salt solution, suitable for MALDI-MS, ≥98.0% (HPLC)

42597

3′-Deoxythymidine 5′-triphosphate sodium salt solution, BioChemika, puriss. p.a., suitable for MALDI-MS, ≥98.0% (HPLC)

MS0100

ProteoMass™ Guanidination Kit, For improving MALDI-MS sensitivity and peptide sequence coverage

MSCAL4

ProteoMass™ MALDI Calibration Kit for Exactive Series MS, LTQ XL and LTQ Hybrids, MALDI MS Calibration Standard

92817

9-Aminoacridine, ≥99.5% (HPLC)

56451

1,5-Diaminonaphthalene, ≥99.0% (HPLC)

50757

Micro-Array for Mass Spectrometry (MAMS), for single cell analysis

94141

4-Chloro-α-cyanocinnamic acid, ≥95.0% (HPLC)

89063

4-Bromo-α-cyanocinnamic acid, ≥95.0% (HPLC)

77081

α-Cyano-4-fluorocinnamic acid, ≥95.0% (HPLC)

38419

α-Cyano-2,3,4,5,6-pentafluorocinnamic acid, ≥95.0% (HPLC)

39379

4-Chloro-α-cyanocinnamic acid - α-Cyano-2,4-difluorocinnamic acid mixture, ≥95.0% (sum of both components, HPLC)

68914

4-Bromo-α-cyanocinnamic acid - 4-Chloro-α-cyanocinnamic acid mixture, ≥95.0% (sum of both components, HPLC)

05851

4-Aminoquinaldine, ≥99.0% (HPLC)

78246

Curcumin, ≥99.5% (HPLC)

04973

Micro-Array for Mass Spectrometry (MAMS), for quantitative MALDI

94477

(E)-2-Cyano-3-(2-naphthyl)acrylic acid, ≥98.0% (HPLC)

83788

(2E)-3-(9-Anthryl)-2-cyanoacrylic acid, ≥97.0% (HPLC)

76884

Anthranilamide, ≥99.0% (HPLC)

56229

9-Nitroanthracene, ≥98.5% (HPLC)

PFS11

SpheriCal™ Mix, Peptide Low, suitable for MALDI-MS

PFS31

SpheriCal™ Aqua, Peptide Medium, suitable for MALDI-MS

PFS32

SpheriCal™ Aqua, Peptide High, suitable for MALDI-MS

PFS20

SpheriCal™ Neat, Peptide Low, suitable for MALDI-MS

PFS21

SpheriCal™ Neat, Peptide Medium, suitable for MALDI-MS

PFS22

SpheriCal™ Neat, Peptide High, suitable for MALDI-MS

PFS23

SpheriCal™ Neat, Protein Low, suitable for MALDI-MS

PFS30

SpheriCal™ Aqua, Peptide Low, suitable for MALDI-MS

69028

4-Phenyl-α-cyanocinnamamide, ≥98.5% (HPLC)

900666

Bruker standard solvent, suitable for MALDI-MS, 50% ACN + 47.5% H2O + 2.5% TFA

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCG2540
    BCBT0674

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    J Wang et al.
    Journal of agricultural and food chemistry, 47(5), 2009-2015 (1999-12-20)
    Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a powerful new technique that will have a great impact on food analysis. This study is the first to demonstrate the applicability of MALDI-MS to perform both qualitative and quantitative analyses of anthocyanins
    U Pieles et al.
    Nucleic acids research, 21(14), 3191-3196 (1993-07-11)
    We report the analysis and characterization of natural and modified oligonucleotides by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). The present technology was highly improved for this class of compounds by using a new matrix, 2,4,6-trihydroxy acetophenone, together
    Tao Wang et al.
    The Analyst, 146(1), 289-295 (2020-11-04)
    Although the in vivo metabolic pathways of scutellarin, a traditional Chinese medicine, have been investigated via different liquid chromatography techniques, studies on the distribution and location of scutellarin within organ tissue sections have not been reported. Matrix-assisted laser desorption/ionization mass
    D I Papac et al.
    Analytical chemistry, 68(18), 3215-3223 (1996-09-15)
    2,5-Dihydroxybenzoic acid (DHB) is the most commonly used matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI/TOF) of oligosaccharides. Because acidic, sialylated oligosaccharides are detected at only the low picomole level with DHB, alternative matrices were screened to identify a
    Analysis of acidic oligosaccharides and glycopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Papac, Damon I., Anissa Wong, and Andrew JS Jones.
    Analytical Chemistry, 68.18, 3215-3223 (1996)
    View All Related Papers

    Protocols

    Mass Spectrometry of Glycans

    Explore mass spectrometry analysis of glycans for glycomic & glycoproteomic neutral & acidic glycan analysis. See a general mass spec glycan analysis procedure.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service