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C8857

ProteoMass™ Cytochrome c MALDI-MS Standard

vial of 10 nmol, (M+H+) 12,361.96 Da by calculation

Synonym(s):

Cytochrome c from equine heart, Cytochrome c from horse heart

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About This Item

CAS Number:
9007-43-6
UNSPSC Code:
12352202
NACRES:
NA.24
MDL number:
MFCD00130890

Key Documents

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Product Name

ProteoMass™ Cytochrome c MALDI-MS Standard, vial of 10 nmol, (M+H+) 12,361.96 Da by calculation

product line

ProteoMass™

form

solid

mol wt

(M+H+) 12,361.96 Da by calculation

packaging

vial of 10 nmol

technique(s)

mass spectrometry (MS): suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Quality Level

100

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Related Categories

Application

Protein calibration standard for MALDI-MS instruments.
The specific sites and extent of oxidation in horse cytochrome c treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.

Biochem/physiol Actions

Cytochrome c is primarily known as an electron-carrying mitochondrial protein. The transition of cytochrome c between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen

Other Notes

View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.

Legal Information

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

wgk

WGK 3

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

动植物来源生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000396617
0000396617
0000396618
0000396618
SLCL7723

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Chung Yeng Looi et al.
BMC complementary and alternative medicine, 13, 166-166 (2013-07-11)
Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called "Kayakalp", commonly applied to treat skin disorders in India and Southeast Asia. Despite its well known anti-inflammatory property on skin
Gabriel Ichim et al.
Molecular cell, 51(5), 632-646 (2013-09-17)
The neurotrophin receptor TrkC was recently identified as a dependence receptor, and, as such, it triggers apoptosis in the absence of its ligand, NT-3. The molecular mechanism for apoptotic engagement involves the double cleavage of the receptor's intracellular domain, leading
Margareta R A Blomberg et al.
Biochimica et biophysica acta, 1827(7), 826-833 (2013-04-27)
The membrane-bound enzyme cNOR (cytochrome c dependent nitric oxide reductase) catalyzes the reduction of NO in a non-electrogenic process. This is in contrast to the reduction of O2 in cytochrome c oxidase (CcO), the other member of the heme-copper oxidase
Chris L Bergstrom et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6269-6274 (2013-04-12)
The release of cytochrome c from mitochondria is a key signaling mechanism in apoptosis. Although extramitochondrial proteins are thought to initiate this release, the exact mechanisms remain unclear. Cytochrome c (cyt c) binds to and penetrates lipid structures containing the
Michaela Wenzel et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(14), E1409-E1418 (2014-04-08)
Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with membranes. To learn how this interaction leads to bacterial death, we characterized the effects of the minimal pharmacophore RWRWRW-NH2. A ruthenium-substituted derivative of this peptide localized to the
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Product Information Sheet - C8857

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