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Key Documents

Safety Information

M-908

Supelco

Midazolam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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1 G
CN¥3,832.67
5 G
CN¥14,190.36

CN¥3,832.67


Available to ship onApril 25, 2025Details


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1 G
CN¥3,832.67
5 G
CN¥14,190.36

About This Item

Empirical Formula (Hill Notation):
C18H13ClFN3
CAS Number:
Molecular Weight:
325.77
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

CN¥3,832.67


Available to ship onApril 25, 2025Details


Request a Bulk Order

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

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Quality Level

100

Quality Level

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Quality Level

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Quality Level

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shipped in

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dry ice

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dry ice

shipped in

-

General description

This Snap-N-Spike® Reference Solution is suitable for testing midazolam by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.
Midazolam is a benzodiazepine drug used for its anxiolytic, muscle relaxant, and anticonvulsant properties.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method-based determination of 12 psychotropic drugs and their metabolites in guinea pig hair samples
  • Multiresidue analysis of 18 benzodiazepines in human blood and hair samples using LC–MS/MS
  • Detection and estimation of 21 benzodiazepines and three z-drugs from human hair samples after their two-step extraction by LC–MS/MS
  • Simultaneous analysis of 54 benzodiazepines and three z-drug residues from human urine and blood samples by ultra high-performance liquid chromatography- triple quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS) method
  • Analysis of 26 compounds, comprising 18 benzodiazepines, seven benzodiazepine metabolites, and one z-drug from dried blood spot (DBS) cards using LC-MS/MS[1]

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number

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Role of midazolam in parkinsonian tremors: to use or not to use.
Tumul Chowdhury et al.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 40(4), 616-616 (2013-08-21)
Context sensitive decrement times of remimazolam.
Thomas Schnider et al.
Anesthesia and analgesia, 117(1), 285-285 (2013-06-22)
W L H Erwin Smelt et al.
Nederlands tijdschrift voor geneeskunde, 157(16), A5941-A5941 (2013-04-19)
Palliative sedation is an effective treatment option in patients with refractory symptoms in the last phase of life. In 2009 the Royal Dutch Medical Association (KNMG) published revised guidelines. The dosage of propofol recommended in these guidelines is, however, based
[Bach instead of midazolam?].
Peter Steifelhagen
Medizinische Monatsschrift fur Pharmazeuten, 36(4), 125-125 (2013-05-10)
E Silay et al.
Nigerian journal of clinical practice, 16(2), 211-215 (2013-04-09)
The aim of our study was to evaluate the likelihood that conscious sedation (CS) with intravenous midazolam could become an alternative modality to general anesthesia (GA) for dental procedures. In our study, 58 and 47 American Society of Anesthesiologists (ASA)-1

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