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Key Documents

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Safety Information

901594

Sigma-Aldrich

Diisopropylcarbodiimide solution

1 M in THF

Synonym(s):

Diisopropylmethanediimine

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1 ML
CN¥838.54

CN¥838.54

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1 ML
CN¥838.54

About This Item

Linear Formula:
C7H14N2
CAS Number:
693-13-0
MDL number:
MFCD00065689
UNSPSC Code:
12352111
NACRES:
NA.22

CN¥838.54

Available to ship onApril 27, 2025Details

Request a Bulk Order

form

liquid

reaction suitability

reaction type: Coupling Reactions

concentration

1 M in THF

density

0.870 g/mL

application(s)

peptide synthesis

SMILES string

N(=C=NC(C)C)C(C)C

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

InChI key

BDNKZNFMNDZQMI-UHFFFAOYSA-N

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This Item
220201C9426C5070
CHAPS 100 mM solution

19899

CHAPS 100 mM solution

CHAPS, Molecular Biology Grade

220201

CHAPS, Molecular Biology Grade

CHAPS hydrate BioReagent, suitable for electrophoresis, ≥98% (HPLC)

C9426

CHAPS hydrate

CHAPS hydrate BioXtra, ≥98% (TLC)

C5070

CHAPS hydrate

technique(s)

protein quantification: suitable

technique(s)

-

technique(s)

electrophoresis: suitable, protein quantification: suitable

technique(s)

protein purification: suitable, protein quantification: suitable

form

liquid

form

crystalline powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

15-25°C

storage temp.

room temp

storage temp.

-

CMC

8 mM

CMC

6 - 10 mM, 6 mM (20-25°C)

CMC

-

CMC

-

transition temp

cloud point >100 °C

transition temp

cloud point >100 °C

transition temp

-

transition temp

-

density

1.01 g/mL at 20 °C

density

-

density

-

density

-

Application

Coupling reagent for peptide syntheses.[1][2][3]
DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.[4]
Valuable reagent offered as a solution in tetrahydrofuran for more convenient handling.

related product

Product No.
Description
Pricing

38370

DIC, purum, ≥98.0% (GC)

D125407

DIC, 99%

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

2.0 °F

Flash Point(C)

-16.66 °C

Regulatory Information

危险化学品
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    MKCX5315
    MKCG2872
    MKCW1383
    MKCR3315

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    Tetrahedron Letters, 35, 5981-5981 (1994)
    Collection of Czechoslovak Chemical Communications, 59, 691-691 (1994)
    Cody L Gilleland et al.
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    Do all traits within an organism age for the same reason? Evolutionary theories of aging share a common assumption: the strength of natural selection declines with age. A corollary is that additive genetic variance should increase with age. However, not
    P J Weber et al.
    Bioorganic & medicinal chemistry letters, 8(6), 597-600 (1999-01-01)
    A new method has been developed to synthesize fluorescein labeled peptides, compounds of increasing importance in bioorganic chemistry, cell biology, pharmacology, drug targeting and medicinal chemistry. We show, that 4(5)-carboxyfluorescein is much more efficient than the hitherto predominantly utilized reagents
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