Skip to Content
Merck
CN
All Photos(3)

Documents

C5070

Sigma-Aldrich

CHAPS hydrate

BioXtra, ≥98% (TLC)

Synonym(s):

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, CHAPS

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C32H58N2O7S · xH2O
CAS Number:
331717-45-4
Molecular Weight:
614.88 (anhydrous basis)
MDL number:
MFCD00012116
UNSPSC Code:
12161900
PubChem Substance ID:
24892750
NACRES:
NA.21

description

zwitterionic

Quality Level

400

product line

BioXtra

Assay

≥98% (TLC)

form

powder

mol wt

614.88 g/mol (anhydrous basis)

technique(s)

protein purification: suitable
protein quantification: suitable

impurities

≤0.001% Phosphorus (P)
≤0.1% Insoluble matter
<0.04% DMF

ign. residue

≤0.1%

mp

157 °C (dec.) (lit.)

solubility

H2O: 0.1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1

InChI key

SJCUTFKCLFLIFE-JWTJKVBLSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.

Application

  • 10mM CHAPS detergent has been used in the process of ion-exchange chromatography for improved purification.
  • 0.5 w/v of CHAPS is a component of high salt buffer in protein purification alongside HEPES, NaCl and EDTA.
  • HEPES buffer has been used as lysis buffer in immunoprecipitation, supplemented with 1% CHAPS.

Not finding the right product?  

Try our Product Selector Tool.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yahya Homsi et al.
FEBS open bio, 7(2), 274-283 (2017-02-09)
Tetraspanins are cell membrane-scaffolding proteins interacting with one another and a repertoire of interaction partners. Through these interactions, they form extended molecular networks as tetraspanin webs or tetraspanin-enriched microdomains. Microscopic data suggest that these networks contain tetraspanin clusters, with poor
Arabidopsis thaliana IRX 10 and two related proteins from psyllium and P hyscomitrella patens are xylan xylosyltransferases.
Jensen JK, et al.
The Plant Journal, 80(2), 207-215 (2014)
The specificity of homomeric clustering of CD81 is mediated by its d-loop.
Homsi Y and Lang T
FEBS Open Bio, 7(2), 274-283 (2017)
Jacqueline M Leung et al.
BMC molecular and cell biology, 21(1), 8-8 (2020-03-01)
TgDCX is a doublecortin-domain protein associated with the conoid fibers, a set of strongly curved non-tubular tubulin-polymers in Toxoplasma. TgDCX deletion impairs conoid structure and parasite invasion. TgDCX contains two tubulin-binding domains: a partial P25α and the DCX/doublecortin domain. Orthologues
Kate E Yu et al.
Molecules and cells, 41(2), 150-159 (2018-02-13)
Animals use their odorant receptors to receive chemical information from the environment. Insect odorant receptors differ from the G protein-coupled odorant receptors in vertebrates and nematodes, and very little is known about their protein-protein interactions. Here, we introduce a mass
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service