- A fast and inexpensive method for N-terminal fluorescein-labeling of peptides.
A fast and inexpensive method for N-terminal fluorescein-labeling of peptides.
Bioorganic & medicinal chemistry letters (1999-01-01)
P J Weber, J E Bader, G Folkers, A G Beck-Sickinger
PMID9871567
ABSTRACT
A new method has been developed to synthesize fluorescein labeled peptides, compounds of increasing importance in bioorganic chemistry, cell biology, pharmacology, drug targeting and medicinal chemistry. We show, that 4(5)-carboxyfluorescein is much more efficient than the hitherto predominantly utilized reagents 4(5)-carboxyfluorescein-N-succinimidylester and 4(5)-fluoresceinisothiocyanate.
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