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900831

Sigma-Aldrich

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

Synonym(s):

Carboxyl diazirine alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):
C8H10N2O2
CAS Number:
Molecular Weight:
166.18
MDL number:
UNSPSC Code:
12352106

form

liquid

Quality Level

reaction suitability

reaction type: click chemistry

availability

available only in USA

storage temp.

−20°C

SMILES string

C#CCCC1(N=N1)CCC(O)=O

Application

Used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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Description
Pricing

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Self-react. C

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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