900862
(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol
Synonym(s):
Hydroxyl diazirine TMS-alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C14H15F3N2OSi
CAS Number:
Molecular Weight:
312.36
UNSPSC Code:
12352200
NACRES:
NA.22
Assay
≥95%
form
powder or crystals
storage temp.
−20°C
SMILES string
OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C
Application
(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
related product
Product No.
Description
Pricing
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Articles
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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