Skip to Content
Merck
CN

900858

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

≥95%

Synonym(s):

Carboxyl diazirine alkyne, Probe building block

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H7F3N2O3
CAS Number:
2187374-12-3
Molecular Weight:
284.19
MDL number:
MFCD31579814
UNSPSC Code:
12352106
NACRES:
NA.22

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, ≥95%

InChI

1S/C12H7F3N2O3/c1-2-5-20-9-6-7(3-4-8(9)10(18)19)11(16-17-11)12(13,14)15/h1,3-4,6H,5H2,(H,18,19)

InChI key

NNGSWZWUOPOVNB-UHFFFAOYSA-N

SMILES string

C#CCOC1=CC(C2(N=N2)C(F)(F)F)=CC=C1C(O)=O

assay

≥95%

form

powder

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Quality Level

100

Related Categories

Application

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCF1622

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service