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81300

Sigma-Aldrich

Poly(ethylene glycol)

average MN 20,000, hydroxyl

Synonym(s):

Polyethylene glycol, PEG

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1 G
CN¥1,006.32
5 G
CN¥3,242.74
25 G
CN¥11,849.43

CN¥1,006.32

List PriceCN¥1,597.73Save 37%

Available to ship onApril 27, 2025Details

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1 G
CN¥1,006.32
5 G
CN¥3,242.74
25 G
CN¥11,849.43

About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24887748
NACRES:
NA.23

CN¥1,006.32

List PriceCN¥1,597.73Save 37%

Available to ship onApril 27, 2025Details

Request a Bulk Order

Product Name

Poly(ethylene glycol), average Mn 20,000

form

flakes

Quality Level

200

mol wt

average Mn 20,000

mp

63-66 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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1 of 4

This Item
D063243816D5545
DL-Dithiothreitol BioUltra, Molecular Biology, ≥99.5% (RT)

43815

DL-Dithiothreitol

DL-Dithiothreitol ≥98% (HPLC), ≥99.0% (titration)

D0632

DL-Dithiothreitol

DL-Dithiothreitol solution BioUltra, Molecular Biology, ~1 M in H2O

43816

DL-Dithiothreitol solution

DL-Dithiothreitol BioXtra, ≥99.0% (titration)

D5545

DL-Dithiothreitol

grade

for molecular biology

grade

-

grade

for molecular biology

grade

-

assay

≥99.5% (RT)

assay

≥98% (HPLC), ≥99.0% (titration)

assay

900-1100 mmol/L (Titration molarity)

assay

≥99.0% (titration)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

product line

BioUltra

product line

-

product line

BioUltra

product line

BioXtra

form

powder

form

powder

form

liquid

form

powder

mp

41-44 °C (lit.)

mp

41-44 °C (lit.)

mp

-

mp

41-44 °C (lit.)

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Application

PEG has been used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.

Photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immunoisolating barriers for encapsulation of cells.[1]

Other Notes

Molecular weight: Mn 16,000-24,000

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCM7806
    BCCM0488
    BCCK9194
    BCCJ4738
    BCCH3137

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    Xu Zhang et al.
    Langmuir : the ACS journal of surfaces and colloids, 28(40), 14330-14337 (2012-09-20)
    Understanding the interface between DNA and nanomaterials is crucial for rational design and optimization of biosensors and drug delivery systems. For detection and delivery into cells, where high concentrations of cellular proteins are present, another layer of complexity is added.
    Chien-Chi Lin et al.
    Biomaterials, 32(36), 9685-9695 (2011-09-20)
    Hydrogels provide three-dimensional frameworks with tissue-like elasticity and high permeability for culturing therapeutically relevant cells or tissues. While recent research efforts have created diverse macromer chemistry to form hydrogels, the mechanisms of hydrogel polymerization for in situ cell encapsulation remain
    Carrie F Olson-Manning
    Molecular biology and evolution, 37(8), 2257-2267 (2020-03-21)
    Metabolic networks are complex cellular systems dependent on the interactions among, and regulation of, the enzymes in the network. Although there is great diversity of types of enzymes that make up metabolic networks, the models meant to understand the possible
    Teagan E Bate et al.
    Soft matter, 15(25), 5006-5016 (2019-06-06)
    Self-organization of kinesin-driven, microtubule-based 3D active fluids relies on the collective dynamics of single microtubules. However, the connection between macroscopic fluid flows and microscopic motion of microtubules remains unclear. In this work, the motion of single microtubules was characterized by
    Oliver J Harrison et al.
    Cell reports, 30(8), 2655-2671 (2020-02-27)
    Non-clustered δ1- and δ2-protocadherins, close relatives of clustered protocadherins, function in cell adhesion and motility and play essential roles in neural patterning. To understand the molecular interactions underlying these functions, we used solution biophysics to characterize binding of δ1- and
    View All Related Papers

    Articles

    Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

    Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

    Versatile Cell Culture Scaffolds: Bio-orthogonal Click

    Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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