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Poly(ethylene glycol)

Name: Poly(ethylene glycol)
Brand: ALDRICH

average M_n 400, hydroxyl

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:

H(OCH₂CH₂)_nOH

CAS Number:

25322-68-3

MDL number:

MFCD00081839

UNSPSC Code:

12352104

PubChem Substance ID:

24852060

NACRES:

NA.23

product name

Poly(ethylene glycol), average M_n 400

form

viscous liquid

Quality Level

200

mol wt

M_n 380-420
average M_n 400

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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refractive index

n20/D 1.466

pH

4.5-7.5

viscosity

7.3 cSt(210 °F)(lit.)

mp

4-8 °C (lit.)

density

1.128 g/mL

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

Aligned,

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Polyethylene Glycol (PEGs and PEOs)

General description

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are non-toxic, FDA-approved, generally non-immunogenic, and frequently used in many biomedical applications including bioconjugation, drug delivery, surface functionalization, and tissue engineering. In drug delivery, PEGs can be used as linkers for antibody-drug conjugates (ADCs) or as a surface coating on nanoparticles to improve systemic drug delivery.

Application

Poly(ethylene glycol) (PEG) has been used as a coating agent for the synthesis and in vitro safety assessment of magnetic bacterial cellulose (MBC) pellicles, performed on porcine aortic smooth muscle cells (PAOSMC). PEG provides a compatible surface for cell culture, since uncoated iron oxide NPs are considered cytotoxic to cells. It has also been used as a plasticizer in investigating the effectiveness of polyvinylpyrrolidone microneedles for transdermal delivery of functional collagen using porcine skin, adult human skin analog and human foreskin. Microneedles obtained, were reportedly characterized by various analytical and bio-analytical techniques.

Solvent for greener fluorination of acetoacetamides with Selectfluor^®.

Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400

Used in conjunction with carbon black to form a conductive composite. Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.

Legal Information

Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany

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Product No.

Description

Pricing

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and in vitro safety assessment of magnetic bacterial cellulose with porcine aortic smooth muscle cells

Pastrana FH, et al.

Journal of Biomedical Materials Research Part A, 104(11), 2801-2809 (2016)

Transdermal delivery of functional collagen via polyvinylpyrrolidone microneedles

Sun W, et al.

Annals of Biomedical Engineering, 43(12), 2978-2990 (2015)

Akashi, M., Akagi, T.

Yuki Gosei Kaguku Kyokaishi, 65, 520-520 (2004)

Simple scaling laws for the evaporation of droplets pinned on pillars: Transfer-rate- and diffusion-limited regimes.

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The evaporation of droplets can give rise to a wide range of interesting phenomena in which the dynamics of the evaporation are crucial. In this work, we find simple scaling laws for the evaporation dynamics of axisymmetric droplets pinned on

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