81275
Poly(ethylene glycol)
tested according to Ph. Eur., 20,000
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Synonym(s):
Macrogol 20,000, Polyethylene glycol, Polyoxyethylene, PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
Agency
tested according to Ph. Eur.
Quality Level
form
flakes
mol wt
16000-24000
application(s)
pharmaceutical (small molecule)
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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General description
Polyethylene glycol (PEG) is a versatile and non-ionic polymer commonly used in a range of industrial and pharmaceutical applications due to its low toxicity, hydrophobic nature, and semicrystalline structure. It is made up of CH2-CH2O repeating units and its ability to exist in both monomer and aqueous phases at high temperatures makes it valuable for a range of research applications.
Application
- Novel fibrous Ag(NP) decorated clay-polymer composite: Implications in water purification contaminated with predominant micro-pollutants and bacteria: This study demonstrates the use of poly(ethylene glycol) (PEG) for the creation of novel fibrous clay-polymer composites, enhancing the removal efficiency of micro-pollutants and bacteria in water treatment systems (Goswami et al., 2024).
- Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol: This review addresses the advances in the uniform production of poly(ethylene glycol) (PEG), critical for its application in drug delivery and pharmaceutical formulations, discussing the material′s solubility, biocompatibility, and stabilization properties (Bento et al., 2024).
- Assessing the structural stability and drug encapsulation efficiency of poly(ethylene glycol)-poly(L-lactic acid) nanoparticles loaded with atorvastatin calcium: The study evaluates the use of PEG in polymeric nanoparticles, focusing on optimizing drug encapsulation efficiency and stability, which is pivotal for effective drug delivery systems (Feng et al., 2024).
- Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes: This research explores the role of PEG in designing responsive nanoscale materials aimed at targeting epigenetic enzymes, showcasing PEG′s versatility in enhancing pharmaceutical applications (Ray et al., 2024).
- Membranes composed of poly(lactic acid)/poly(ethylene glycol) and Ora-pro-nóbis (Pereskia aculeata Miller) extract for dressing applications: This article highlights the application of PEG in developing biocompatible and efficient wound dressing materials, combining poly(lactic acid) and natural extracts to enhance healing processes (Mendes et al., 2024).
Biochem/physiol Actions
Polyethylene glycols (PEGs) or macrogols are broadly used as additives in cosmetics and pharmaceuticals. Addition of this hydrophilic polymer blocks and reverses some types of surfactant inactivation in vitro. PEG can be used as a macroinitiator, stabilizer, or dispersant in the field of emulsion polymerization with the help of its derivatives or modifications.
Features and Benefits
- Environment friendly
- Biocompatible
- Unique solvent solution
WGK
WGK 1
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Polymer nanocomposites for biomedical applications
Rahmani S, et al.
Journal of Separation Science, 175-215 (2022)
Polyethylene glycol/surfactant mixtures improve lung function after HCl and endotoxin lung injuries.
K W Lu et al.
American journal of respiratory and critical care medicine, 164(8 Pt 1), 1531-1536 (2001-11-13)
Addition of nonionic polymers such as polyethylene glycol (PEG) and dextran ameliorates inactivation of Survanta by a variety of substances in vitro. Addition of polymers to Survanta also improves pulmonary function when used to treat rats with lung injury caused
Yiming Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 29(9), 3024-3033 (2013-02-26)
Through zeta potential and surface tension measurements and a series of polymerization experiments, the role of poly(ethylene glycol) (PEG) in the process of surfactant-free polymerization of styrene (St)/methyl methacrylate (MMA) has been investigated experimentally. Nanoscale and stable copolymer particles were
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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