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250 MG
CN¥921.57
1 G
CN¥1,260.06
10 G
CN¥9,181.14
20 G
CN¥16,176.93
50 G
CN¥35,946.28
100 G
CN¥62,923.89
About This Item
线性分子式:
[C6H10(NH2)2]PtCl2
CAS号:
分子量:
380.17
MDL编号:
UNSPSC代码:
12161600
PubChem化学物质编号:
NACRES:
NA.22
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反应适用性
core: platinum
reagent type: catalyst
mp
280 °C (dec.) (lit.)
SMILES字符串
Cl[Pt]Cl.NC1CCCCC1N
InChI
1S/C6H14N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-6H,1-4,7-8H2;2*1H;/q;;;+2/p-2
InChI key
PNNCIXRVXCLADM-UHFFFAOYSA-L
1 of 4
此商品 | 609471 | 488003 | 348465 |
|---|---|---|---|
| technique(s) bio NMR: suitable, protein expression: suitable | technique(s) bio NMR: suitable | technique(s) - | technique(s) - |
| mass shift M+1 | mass shift M+1 | mass shift M+1 | mass shift M+1 |
| isotopic purity ≥98 atom % 15N | isotopic purity 92-97.9 atom % 15N | isotopic purity 60-80 atom % 15N | isotopic purity 10 atom % 15N |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| mp 340 °C (subl.) (lit.) | mp 340 °C (subl.) (lit.) | mp 340 °C (subl.) (lit.) | mp 340 °C (subl.) (lit.) |
警示用语：
Danger
危险分类
Carc. 2 - Eye Dam. 1 - Lact. - Muta. 2 - Repr. 1B - Resp. Sens. 1B - Skin Sens. 1 - STOT RE 1
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
G R Gibbons et al.
Cancer research, 49(6), 1402-1407 (1989-03-15)
Tetrachloro(D,L-trans)1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) is a new platinum analogue which is less nephrotoxic than cisplatin and is effective in some cell lines which have become resistant to cisplatin. Since platinum(IV) compounds are thought to require reduction to their platinum(II) analogues for activity
H Cabral et al.
Nature nanotechnology, 6(12), 815-823 (2011-10-25)
A major goal in cancer research is to develop carriers that can deliver drugs effectively and without side effects. Liposomal and particulate carriers with diameters of ∼100 nm have been widely used to improve the distribution and tumour accumulation of cancer
Siden Top et al.
Chembiochem : a European journal of chemical biology, 4(8), 754-761 (2003-08-05)
The goal of our study was to potentiate the effects of the ((R,R)-trans-1,2-diaminocyclohexane)-platinum(II) fragment [(DACH)Pt], known for its cytotoxic properties, either with tamoxifen (Tam), the most widely used antiestrogen in the treatment of hormone-dependent breast cancers, or with its active
V Boudný et al.
Nucleic acids research, 20(2), 267-272 (1992-01-25)
Modification of DNA and double-stranded deoxyoligonucleotides with antitumour 1,2-diamino-cyclohexanedinitroplatinum(II) (Pt-dach) complexes was investigated with the aid of physico-chemical methods and chemical probes of nucleic acid conformation. The three Pt-dach complexes were used which differed in isomeric forms of the dach
P F Carfagna et al.
Cancer chemotherapy and pharmacology, 27(5), 335-341 (1991-01-01)
Plasma biotransformations of tetrachloro(d,l-trans)1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) were determined in vivo at both therapeutic (3 mg/kg) and toxic (12 mg/kg) doses in Fischer 344 rats. Tetraplatin was rapidly converted to dichloro(d,l-trans)1,2-diaminocyclohexaneplatinum(II) [PtCl2(dach)]. This conversion was complete at the earliest time measured (7.5
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