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Merck
CN

COL1A1

collagen, type I, alpha 1

别名:
OI4
物种:
UniProtKB ID:
基因ID:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

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Antibodies

货号
说明
物种反应性
应用
单克隆抗-胶原蛋白,I型 小鼠抗, clone COL-1, ascites fluid,
物种反应性
bovine, deer, human, pig, rabbit, rat
应用
ELISA
dot blot

immunohistochemistry
抗I型胶原蛋白抗体,小鼠单克隆, clone COL-1, purified from hybridoma cell culture,
物种反应性
bovine, deer, human, pig, rat
应用
ELISA
dot blot

immunohistochemistry

western blot
抗I型前胶原抗体,NT,克隆M-58, culture supernatant, clone M-58, Chemicon®,
物种反应性
human
应用
immunohistochemistry
抗小鼠I型胶原抗体, Chemicon®, from rabbit,
物种反应性
mouse
应用
ELISA
immunohistochemistry

radioimmunoassay

western blot
抗-COL1A1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Proteins

货号
说明
物种
I型胶原蛋白 溶液 来源于大鼠尾, BioReagent, suitable for cell culture, sterile-filtered,
物种
rat
I型胶原,大鼠尾巴, ,
物种
rat
胶原蛋白 来源于大鼠尾, Bornstein and Traub Type I, powder, BioReagent, suitable for cell culture,
物种
rat
胶原, from rat tail tendon,
物种
rat
人胶原蛋白 Ⅰ 型, ,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Col1a1,
物种
mouse
MISSION® esiRNA, targeting human COL1A1,
物种
human