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Merck
CN

1563502

USP

Procainamide hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide

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About This Item

Linear Formula:
H2NC6H4CONHCH2CH2N(C2H5)2·HCl
CAS Number:
614-39-1
Molecular Weight:
271.79
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750955
MDL number:
MFCD00012998
Beilstein/REAXYS Number:
3729517

Key Documents

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Product Name

Procainamide hydrochloride, United States Pharmacopeia (USP) Reference Standard

InChI key

ABTXGJFUQRCPNH-UHFFFAOYSA-N

SMILES string

Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1

InChI

1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H

grade

pharmaceutical primary standard

API family

procainamide

manufacturer/tradename

USP

mp

167-169 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Procainamide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Procainamide Hydrochloride Injection

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Nenad Manevski et al.
Drug metabolism and disposition: the biological fate of chemicals, 43(1), 126-139 (2014-10-24)
Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fresh full-thickness human skin explants

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