Skip to Content

关于应对近期政策变化的重要更新，请点击此处查看详情。

Merck
CN
All Photos(1)

Key Documents

Safety Information

SRP3196

Sigma-Aldrich

EGF from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Synonym(s):

Epidermal Growth Factor, URG, Urogastrone

Sign Into View Organizational & Contract Pricing

Select a Size

1 MG
CN¥669.75
5 MG
CN¥2,560.22
10 MG
CN¥4,050.78

CN¥669.75

Estimated to ship onJuly 02, 2025Details

New, lower price on this item!
All Photos(1)

Select a Size

Change View
1 MG
CN¥669.75
5 MG
CN¥2,560.22
10 MG
CN¥4,050.78

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

CN¥669.75

Estimated to ship onJuly 02, 2025Details

New, lower price on this item!

biological source

mouse

recombinant

expressed in E. coli

Assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

potency

0.1 ng/mL

mol wt

6.0 kDa

packaging

pkg of 500 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

off-white to yellow

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
171006117100981710044
ChIPAb+ TCF-4 - ChIP Validated Antibody and Primer Set from mouse

1710109

ChIPAb+ TCF-4 - ChIP Validated Antibody and Primer Set

ChIPAb+ E2F-1 - ChIP Validated Antibody and Primer Set from mouse

1710061

ChIPAb+ E2F-1 - ChIP Validated Antibody and Primer Set

ChIPAb+ TATA Binding Protein (TBP) - ChIP Validated Antibody and Primer Set ascites fluid, from mouse

1710098

ChIPAb+ TATA Binding Protein (TBP) - ChIP Validated Antibody and Primer Set

ChIPAb+ CTCF - ChIP经验证的抗体和引物组 clone 1.2.1.5.4, from mouse

1710044

ChIPAb+ CTCF - ChIP经验证的抗体和引物组

species reactivity

human, mouse

species reactivity

human, Xenopus

species reactivity

human, zebrafish, mouse, Xenopus, chicken, fish

species reactivity

human

clone

monoclonal

clone

monoclonal

clone

monoclonal

clone

1.2.1.5.4, monoclonal

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

technique(s)

ChIP: suitable, immunoprecipitation (IP): suitable, dot blot: suitable, western blot: suitable

technique(s)

ChIP: suitable (ChIP-seq), immunoprecipitation (IP): suitable

technique(s)

ChIP: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

ChIP: suitable, ELISA: suitable, dot blot: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, multiplexing: suitable, western blot: suitable

Gene Information

human ... TCF7L2(6934)

Gene Information

-

Gene Information

human ... TBP(6908)

Gene Information

human ... CTCF(10664)

General description

EGF (epidermal growth factor) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells.[1] Recombinant murine EGF is a 6kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.

Application

EGF from mouse has also been used in the DMEM/F12 media for growing mouse kidney cells.[2]

Biochem/physiol Actions

EGF (epidermal growth factor) has been shown to inhibit gastric secretion, and to be involved in wound healing.[3][4] EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor.[5] This receptor also binds with TGF (transforming growth factor)-α and VGF (vaccinia virus growth factor). EGF plays an important role in embryogenesis and cardiogenesis.[6][7]

Sequence

NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR

Physical form

Lyophilized from 10 mM Sodium Phosphate, pH 8.2.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0324179
    0623179
    623179
    1022179-1
    0422179-1

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease.
    Menezes LF
    EBioMedicine, 5, 183-192 (2016)
    Requirement of Leukemia Inhibitory Factor or Epidermal Growth Factor for Pre-Implantation Embryogenesis via JAK/STAT3 Signaling Pathways.
    Cheng EH
    PLoS ONE, 11, e0153086-e0153086 (2016)
    EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner.
    Ma CX
    Cellular and Molecular Life Sciences, 72, 2005-2022 (2015)
    Epidermal growth factor therapy and wound healing--past, present and future perspectives.
    Hardwicke J
    The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 6, 172-177 (2008)
    Transforming growth factor alpha and epidermal growth factor in protection and healing of gastric mucosal injury.
    Konturek SJ
    Scandinavian Journal of Gastroenterology, 27, 649-655 (1992)
    View All Related Papers

    Articles

    3D Organoid Culture: New In Vitro Models of Development and Disease

    Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service