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Key Documents

Safety Information

SAB4502012

Sigma-Aldrich

Anti-INOS antibody produced in rabbit

affinity isolated antibody

Synonym(s):

INDUCIBLE, MACROPHAGE, NITRIC OXIDE SYNTHASE, NOS2A

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25 G
¥1,008.93

¥1,008.93

Estimated to ship on2025年5月22日Details

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25 G
¥1,008.93

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

¥1,008.93

Estimated to ship on2025年5月22日Details

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 131 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

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63177

6-(马来酰亚胺基)己酸琥珀酰亚胺酯

4-马来酰亚胺基丁酸 N -羟基琥珀酰亚胺酯 ≥98.0% (HPLC)

63175

4-马来酰亚胺基丁酸 N -羟基琥珀酰亚胺酯

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

reaction suitability

reagent type: linker

reaction suitability

reagent type: linker

reaction suitability

reagent type: linker

reaction suitability

reagent type: linker

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

form

solid

form

powder

form

solid

form

-

mp

167-171 °C

mp

168-170 °C (lit.)

mp

67-73 °C, 70-73 °C (lit.)

mp

123-129 °C

General description

Anti-INOS antibody detects endogenous levels of total INOS protein.
The INOS (inducible nitric oxide synthase) gene is mapped to human chromosome 17q11.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human iNOS.

Immunogen Range: 1101-1150

Application

Anti-INOS, C-Terminal antibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Upregulation of INOS (inducible nitric oxide synthase) is observed during infections, tissue injury, and inflammation. INOS is responsible to produce NO (nitric oxide), which controls blood flow by inducing vascular relaxation. NO acts as a neurotransmitter and can facilitate immune responses. NO can also bring about anti-thrombotic and anti-inflammatory effects in response to oxidative stress, hypoxia, inflammatory cytokines (TNF-α, IL-1β, IFN-γ), and lipopolysaccharide endotoxin. iNOS generates more NO than the neuronal and endothelial NOS. Unlike the two isoforms, iNOS is calcium independent. INOS might be associated with type 2 diabetes mellitus.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Lot/Batch Number
    310251

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