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安全信息

SAB5500152

Sigma-Aldrich

Anti-INOS antibody, Rabbit monoclonal

clone SP126, recombinant, expressed in proprietary host, affinity isolated antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

重组

expressed in proprietary host

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

SP126, monoclonal

种属反应性

human (tested)

种属反应性(根据同源性预测)

rat

技术

immunohistochemistry: 1:100

同位素/亚型

IgG

UniProt登记号

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

human ... NOS2(4843)

一般描述

Inducible NOS (iNOS) or macrophage NOS (mNOS) is calcium/calmodulin independent and is expressed in activated macrophages and stimulated glial cells. NOS oxidizes a guanidine nitrogen of arginine, releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation, neurotransmission, anti-tumor and anti-pathogenic activities.

免疫原

Synthetic peptide near the C-terminus of mouse iNOS protein.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

含少量动物源组分生物产品
常规特殊物品

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Analytical cellular pathology (Amsterdam), 2020, 5424780-5424780 (2020-09-05)
Tumor-associated macrophages (TAMs) and tumor-infiltrating lymphocytes (TILs) contribute significantly to the development of immunosuppressive properties of a tumor. In this study, we performed immunohistochemical analysis of immune cells of esophageal tumors stroma. Paraffin-embedded tissue specimens from 48 esophageal squamous cell
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International journal of molecular sciences, 22(1) (2021-01-21)
There is an urgent need for identification of new prognostic markers and therapeutic targets for non-small cell lung cancer (NSCLC). In this study, we evaluated immune cells markers in 100 NSCLC specimens. Immunohistochemical analysis revealed no prognostic value for the
Olga Kovaleva et al.
Biomedicines, 8(9) (2020-09-17)
The link between a lung tumor and the lung microbiome is a largely unexplored issue. To investigate the relationship between a lung microbiome and the phenotype of an inflammatory stromal infiltrate, we studied a cohort of 89 patients with non-small
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Biomedicines, 9(7) (2021-07-03)
Esophageal cancer is one of the most aggressive malignant neoplasms, with low survival rates and limited treatment options. In this study we analyzed the microbiome composition and the phenotype of inflammatory tumor infiltrate in squamous cell carcinoma of esophagus (ESCC)

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