产品名称
抗-INOS 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 131 kDa
species reactivity
rat, human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NOS2(4843)
Biochem/physiol Actions
在感染、组织损伤和炎症期间观察到INOS（诱导型一氧化氮合酶）的上调。INOS负责产生NO（一氧化氮），通过诱导血管舒张来控制血流。NO充当神经递质，可以促进免疫反应。NO还可以响应氧化应激、缺氧、炎性细胞因子（TNF-α，IL-1β，IFN-γ）和脂多糖内毒素而产生抗血栓形成和抗炎作用。iNOS比神经元和内皮NOS产生更多的NO。与这两种同工型不同，iNOS与钙无关。INOS可能与2型糖尿病有关。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
General description
INOS（诱导型一氧化氮合酶）基因定位于人类染色体17q11.2。
抗-INOS抗体可检测内源性总INOS蛋白水平。
Immunogen
该抗血清是针对衍生自人iNOS的合成肽而生成的。
免疫原范围： 117-166
免疫原范围： 117-166
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Yan Yang et al.
Molecular medicine reports, 13(2), 1220-1226 (2015-12-10)
Spinal nitric oxide is involved in the mechanisms of pain generation and transmission during inflammatory and neuropathic pain. The aim of the present study was to explore the role of spinal nitric oxide in the development of bone cancer pain.
Feng Chen et al.
IUBMB life, 68(7), 516-525 (2016-05-20)
Inducible nitric oxide synthase (NOS2) and endothelial nitric oxide synthase (NOS3) gene play important roles in the susceptibility to type 2 diabetes mellitus (T2DM). The present study aims to detect the potential association of NOS2 and NOS3 gene polymorphisms with
Mateusz Adamiak et al.
Stem cell reviews, 13(1), 92-103 (2016-10-19)
Nitric oxide (NO) is a gaseous free radical molecule involved in several biological processes related to inflammation, tissue damage, and infections. Based on reports that NO inhibits migration of granulocytes and monocytes, we became interested in the role of inducible
R A Lea et al.
American journal of medical genetics, 105(1), 110-113 (2001-06-27)
Migraine is a debilitating disorder affecting approximately 12% of Caucasian populations. The disease has a large genetic component, although at present the type and number of genes involved is unclear. Candidate gene studies may be useful strategies for identifying genes
Abhilash Vijay Nair et al.
Redox biology, 72, 103151-103151 (2024-04-10)
Salmonella infection entails a cascade of attacks and defence measures. After breaching the intestinal epithelial barrier, Salmonella is phagocytosed by macrophages, where the bacteria encounter multiple stresses, to which it employs relevant countermeasures. Our study shows that, in Salmonella, the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持