推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 131 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... NOS2(4843)
一般描述
INOS（诱导型一氧化氮合酶）基因定位于人类染色体17q11.2。
抗-INOS抗体可检测内源性总INOS蛋白水平。
免疫原
该抗血清是针对衍生自人iNOS的合成肽而生成的。
免疫原范围： 1101-1150
免疫原范围： 1101-1150
应用
兔抗INOS，C端抗体可用于免疫印迹。
生化/生理作用
在感染、组织损伤和炎症期间观察到INOS（诱导型一氧化氮合酶）的上调。INOS负责产生NO（一氧化氮），通过诱导血管舒张来控制血流。NO充当神经递质，可以促进免疫反应。NO还可以响应氧化应激、缺氧、炎性细胞因子（TNF-α，IL-1β，IFN-γ）和脂多糖内毒素而产生抗血栓形成和抗炎作用。iNOS比神经元和内皮NOS产生更多的NO。与这两种同工型不同，iNOS与钙无关。INOS可能与2型糖尿病有关。
特点和优势
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
外形
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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